GLP-1 & your hair
Pumpkin Seed Oil or Saw Palmetto for GLP-1 Hair Loss? 5 Bottles, Ranked
On the shot or about to start? Can you take them with the shot, and which of 5 bottles has the right amounts?
- When the shot takes fat off fast, some estrogen goes with it. That lets DHT thin the top. DHT is a hormone that shrinks hair roots.
- Two plants have been studied for slowing DHT: pumpkin seed oil and saw palmetto, a palm berry.
- Number one has 1,000 mg of pumpkin seed oil and 320 mg of saw palmetto, with low biotin.
Both, in one bottle. They're the two plants studied for slowing DHT, a hormone that thins hair on top.
No GLP-1 shot is on the list of drugs known to mix badly with saw palmetto. Taking a blood thinner, birth control pills or hormone therapy? Show your pharmacist the label.
Somebody told you about pumpkin seed oil and saw palmetto. Maybe a friend on the shot, or a post you read late at night.
Now you have two questions. Can you take them with the shot? And which bottle is worth it?
If you're on the shot, your brush may already be full of hair. If you’re about to start, you want to get ahead of it.
Why the top thinsWhat's going on
Your body makes two hormones that matter for the hair on top. Estrogen is one. Every woman makes it, and one of its jobs is guarding the hair roots.
The other is DHT. Your body makes it from testosterone, which women make a little of too. DHT shrinks the hair roots on top, so each new hair comes in thinner.
The two pull against each other. While estrogen is up, DHT loses. When estrogen drops, DHT wins on top.
On a GLP-1, that happens in three steps.
- 1Fat makes some of your estrogen
Body fat is one of the places your body makes estrogen.
- 2The shot takes fat fast
Less fat means less estrogen guarding the roots on top.
- 3The top thins, the back doesn't
DHT shrinks the roots on top, but the back stays thick.
How it startsHow you got here
The weight comes off. Then, around month 3, the hair starts falling out.
You see more in your brush and in the drain. Everyone has advice: eat more protein, take biotin, wait it out.
Protein protects your muscle, so keep eating it. But it does nothing for DHT.
So you started reading about DHT. Two plants kept coming up: pumpkin seed oil and saw palmetto.
I'm terrified of losing my hair.
A woman on the shot
Then you go to buy some. A lot of the bottles are sold to men, for the prostate.
Not on the shot yet? Then you have time to start before month 3.
The checks5 things to look for on the label
What to look for
Here's what to look for on the back of the bottle.
- Made for women. The front says it's for women, not men.
- Real pumpkin seed oil. A full 1,000 mg a day, with the amount printed.
- Saw palmetto, with its amount. 320 mg, printed on its own, not hidden in a “blend.”
- Easy on blood tests. Low biotin and no iodine, so your blood tests stay accurate.
- Minerals for the root. Zinc, selenium and copper, with the amounts printed.
We checked every bottle below on these same five things.
The rankingThe 5 bottles, worst to best
These are the pumpkin seed oil and saw palmetto bottles women reach for. We checked each one on the same 5 things, straight off the label.
The other four got two right each. Only one got all five.
✓ Gets it right · ✕ Problem · ! Okay, not ideal
Swanson Pumpkin Seed Oil 1,000 mg
100 softgels
Gets 2 of 5 right- Made for Men. It's sold for the prostate
- Pumpkin seed oil 1,000 mg of real oil
- Saw palmetto None
- Blood tests No biotin, no iodine
- For the root No zinc, selenium or copper
- Price About $16 for 100 softgels
Verdict. A full 1,000 mg of pumpkin seed oil, and cheap. But it's sold to men, for the prostate. And it has no saw palmetto.
NOW Pumpkin Seed Oil 1,000 mg
2 softgels, once or twice a day
Gets 2 of 5 right- Made for General health, not women or hair
- Pumpkin seed oil 1,000 mg a softgel, cold-pressed
- Saw palmetto None
- Blood tests No biotin, no iodine
- For the root No zinc, selenium or copper
- Price About $12 for 100 softgels
Verdict. Real cold-pressed pumpkin seed oil, and cheap. But there's no saw palmetto and no minerals. And nothing on the bottle says it's for women or hair.
NOW Saw Palmetto Extract 320 mg
1 softgel a day
Gets 2 of 5 right- Made for Men's health, the prostate
- Pumpkin seed oil 80 mg, a small amount
- Saw palmetto 320 mg, printed
- Blood tests No biotin, no iodine
- For the root No zinc, selenium or copper
- Price Under $15 a month
Verdict. A full 320 mg of saw palmetto, and cheap. But only 80 mg of pumpkin seed oil. And it's made for men.
Vegamour GRO+ Advanced Hair Supplements
3 pills a day
Gets 2 of 5 right- Made for Anyone, not just women
- Pumpkin seed oil 400 mg of an extract, not the oil
- Saw palmetto 320 mg, printed
- Blood tests Biotin 2,000 mcg
- For the root Zinc, selenium and copper
- Price About $78 to $88 a month
Verdict. The closest to number one, with both plants printed. But it has 2,000 mcg of biotin, 20 times number one's. And one month costs more than 12 weeks of number one.
HALO Hair
2 softgels a day
Gets 5 of 5 right- Made for Women losing hair on top
- Pumpkin seed oil 1,000 mg, cold-pressed
- Saw palmetto 320 mg, printed
- Blood tests Biotin 100 mcg, no iodine
- For the root Zinc, selenium and copper
- Price $20 a bottle when you buy 3
Verdict. The only one here that gets all five right. It has 1,000 mg of cold-pressed pumpkin seed oil, 320 mg of saw palmetto and low biotin. It's made for thinning on top, on the shot or before you start.
Prices and labels checked September 2026.
Get number one, buy 2 get 1 free →Every amount on the label. Free US shipping on 3 bottles.
Number oneWhat's inside number one, and how it works
You take two softgels a day. Here's everything in them, and how much.
| Ingredient | Per day | What it does |
|---|---|---|
| Pumpkin seed oil, cold-pressed | 1,000 mg | Slows how much DHT is made at the root |
| Saw palmetto extract | 320 mg | Does the same job, in a different way |
| Zinc | 10 mg | A mineral hair roots use to grow |
| Selenium | 55 mcg | Helps protect the cells at the root |
| Copper | 1 mg | A mineral hair needs |
| Vitamin E | 50 mg | Helps protect cells from wear and tear |
| Biotin | 100 mcg | Low on purpose, so blood tests stay accurate |
| Iodine | None | Left out, so thyroid tests stay accurate |
Every amount is printed on the label, with no blend.
How it works
Estrogen helps guard the roots on top. On the shot, you lose some of it along with the fat.
Women make a little testosterone too. At the root, a natural switch called an enzyme turns some of it into DHT.
Both plants slow that switch. So less DHT reaches the roots on top.
Each plant does it in its own way. You don't need a prescription.
Where it comes from
Pumpkin seed oil is pressed cold from the seeds, like good olive oil. Saw palmetto is the berry of a small palm that grows wild in Florida.
What the research says
There's one small study, and it was in men. They took 400 mg of pumpkin seed oil a day for 24 weeks.
At the end, doctors counted about 40% more hairs. Men on a sugar pill had about 10% more.
There's no study in women yet. Number one has 1,000 mg of the oil a day.
What makes it different
It's the only one here with 1,000 mg cold-pressed pumpkin seed oil and 320 mg saw palmetto.
The biotin is kept low, at 100 mcg, and there's no iodine. It's made for women losing hair on top, on the shot or about to start.
See the full label →Your bottleNow check yours
Got a bottle at home? Check the back for the same five things:
- Is it made for women, or for the prostate?
- Is there 1,000 mg of real pumpkin seed oil?
- Is the saw palmetto amount printed, not hidden in a blend?
- Is the biotin low, with no iodine?
- Are zinc, selenium and copper on it?
Count how many it gets right.
If yours got fewer than five, that's not your fault. You bought it off the same shelf as everyone else.
What it costs
It costs more than plain pumpkin seed oil. Buy two and the third is free, so it comes to $20 a bottle.
What number one costs
Buy once, or subscribe and save from $24.99. Free US shipping on 3 or more. 90-day money back.
QuestionsWhat women on the shot ask
Can I take saw palmetto or pumpkin seed oil with a GLP-1?
No GLP-1 shot is on the list of drugs known to mix badly with saw palmetto. Taking a blood thinner, birth control pills or hormone therapy? Show the label to your pharmacist. If you take iron pills, take them two hours apart from number one.
Is pumpkin seed oil a DHT blocker?
It's one of the two plants studied for DHT. It slows the switch at the root that makes DHT. The one study on hair was in men.
How much pumpkin seed oil should a woman take?
No study in women has set an amount. The one study, in men, used 400 mg a day. Number one has 1,000 mg.
Pumpkin seed oil or saw palmetto?
Both, if you can. Each one slows the same switch in a different way. Look for one bottle with both amounts printed.
Does saw palmetto have side effects?
Most people take it without trouble. The usual complaints are mild, like an upset stomach, dizziness or a headache. If your period changes, tell your doctor. Don't take it if you're pregnant or breastfeeding.
Or you close this page. That's allowed.
The weight keeps coming off, and month 3 gets closer.
At first, nothing seems different. Then you see more hair in your brush.
You know the five things to look for now. You'll decide for yourself.
Get number one, buy 2 get 1 free →Buy once, or subscribe and save.
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